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Central Scheme for Evolving Pharmacopoeial Standards for Ayurveda, Siddha, Unani and Homoeopathy drugs and Standardized Operating Procedures (SOPs) of Manufacturing Processes of ASU&H drugs.

sting Pharmocopoeia work in Ayurveda Siddha, Unani and Homoeopathy ishave published standards on single drugs andDownload complete
 Manufacturing Processes of ASU&H drugs.
a) The Government of India set up the Ayurvedic, Siddha, Unani and Homoeopathic
Pharmacopoeia committees in the year 1962, 1975 & 1964 & 1962 respectively. These four
committees are supported technically by the Pharmacopoeial Laboratory for Indian Medicine
(PLIM) and Homoeopathic Pharmacopoeia Laboratory situated at Ghaziabad which are apex
laboratories dedicated to developing Pharmacopoeial Standards of Indian and Homoeopathic
Medicine. The exi
being done presently by these Committees which
multi ingredient formulations of Ayurvedic , Siddha, Unani and Homoeopathy. There are about
2000 single drugs and an equal number of compound formulations where standards are yet to be

b) Ayurveda, Siddha, Unani and Homeopathy drugs consist of various kinds of formulations
prepared from plants, minerals, metals, animal and marine products as raw material. These
formulations are prepared after various kinds of processing with the specific methods prescribed in
these systems. These formulations are grouped in various dosage form according to their method of
preparation, palatability, bioavailability and theraeuptic values accordingly their nomenclature is
given in texts mentioned in Drugs and cosmetic Act. 1940 viz Avleh, churna, Asava, Bhasma,
Ghrita, Taila, Kupipakva, Gutika, Guggulu Modaka, Louh, Pisti etc. in Ayurveda. Churanam,
Parpan, Chinduam, Kudnar, Mathrai in Siddha and Kushta, Majoon, Hubb, Safoof etc. in Unani,
Nosodes, Sarcodes in Homoeopathic Systems of Medicines.

c) The National health Policy on AYUSH, 2002 reiterated the importance of Pharmacopoeial
work related to Ayurveda, Siddha, Unani and Homoeopathy Drugs and had emphasised on its
expeditious implementation. Although, significant achievements have been made by the existing
pharmacopoeia set up, a need has been felt to have
better coordination and results. Consequently,
developed through studies conducted both through in- house laboratories and through
laboratories/institutions accredited by Government through two a stage bidding system. Therefore,
 unified pharmacopoeial infrastructure forPharmacopoeial standards are proposed to behe work of these individual pharmacopoeial committees will be subsumed in the instant scheme.

Clinical evaluation of some predefined homoeopathic medicines in osteoarthritis


Osteoartrhitis Knee
 Objectives: The objectives of the study were to clinically evaluate efficacy of some predefined homoeopathic drug(s), selected on the basis of their traditionally/empirically use as mentioned in the literature: Bryonia alba, Rhus toxicodendron, Formica rufa, Calcarea carbonica, Causticum, Thuja occidentalis, Guaiacum, Lycopodium clavatum, Medorrhinum, Calcarea fluoricum and Osteoarthritis Nosode and also to evaluate their efficacy in relieving the signs and symptoms of Osteoarthritis, their most useful potencies, frequency of administration, and their relationship with other medicines..

Methods: It was a multi-centric observational study (Open clinical trial) carried out by Central Council for Research in Homoeopathy at its Regional Research Institute (Homoeopathy), Gudivada, Andhra Pradesh (1995-2005) and Clinical Research Unit (Homoeopathy), Patiala, Punjab (1985-1994). A total number of 508 cases of primary Osteoarthritis (localized) were selected according to the pre-defined parameters. The detailed case recording was done for each case and after matching the symptoms of the patient with one of the 11 drugs, the most similimum medicine was prescribed and the cases were monitored for assessing the improvement status according to the pre-defined criteria and the results were evaluated.

Results: Out of 508 cases followed up, 453 cases improved in varying degrees; marked improvement in 69 cases, moderate improvement in 150 cases and mild improvement in 234 cases. No improvement was seen in 9 cases. The intervention drugs were found effective in relieving the symptoms & signs of osteoarthritis when prescribed as per their indications: Bryonia alba (n=115), Calcarea carbonica (n=27), Calcarea fluoricum (n=9), Causticum (n=45), Formica rufa (n=67), Guaiacum (n=16), Lycopodium clavatum (n=21), Medorrhinum (n=7), Rhus toxicodendron (n=109) and Thuja occidentalis (n=15).

Conclusion: Outcome of the study shows that homoeopathic medicines are effective in managing osteoarthritis. Other objectives of the study which included most useful potencies of medicines, their frequency of administration and relationship with other medicines could not be achieved. However, further study with predefined biochemical and radiological markers needs to be conducted. Also osteoarthritis nosode had not been prescribed to any patient in the study, and a separate detailed trial needs to be conducted.

G.C. Sahagal, Bhawan Singh
Clinical Research Unit Patiala.

K. Bhanumurty, Ch. Raveendar
Regional Research Institute, Gudivada.

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Clinical evaluation of predefined homoeopathic medicine in the treatment of vitiligo

Objectives: The objective of the study was to ascertain the role of predefined homoeopathic medicine (Ars. sulph. flavum) selected on the basis of its traditional/empirical use as mentioned in the literature in the treatment of vitiligo and to identify its reliable indications, most useful potencies, frequency of administration and to observe its relationship with other medicines.

Methods: Central Council for Research in Homoeopathy conducted this study at Clinical Research Unit (H), Tirupathi (Andhra Pradesh) from 1987 to 2003. This observational clinical trial was conducted on 282 patients involving 137 males and 145 females. The cases of both sexes and all age groups were included in the study on the basis of presence of subjective or objective symptoms, guiding to the diagnosis of vitiligo and other predefined parameters. The prescriptions were made after detailed case taking as per homoeopathic principles.

Results: Two hundred and seven cases were followed up regularly. In 59 cases other medicines apart from Ars. sulph. flav. were used as per their indications. One case was cured completely and varying degrees of improvement were observed in 181 cases (marked, n=25, moderate, n=52, mild, n=104), 25 cases showed no improvement. Ars. sulph. flav. was found to be effective in 154 out of 223 (69%) cases. The other drugs, which have shown better results in the study, are: Ars. alb. (n=9) and Nitric acid (n=13). Indicated homoeopathic medicines in 3x, 6x, 30, 200 and 1M potencies were found to be effective. Syphillinum was used as an intercurrent medicine to Ars. sulph. flav. in 36 cases and was found effective in all the cases.

Conclusion: Trial medicine has been found effective in the treatment of vitiligo to some extent with limited outcome parameters. The objectives to identify its reliable indications, most useful potencies and the intercurrent relationship with other medicines could be accomplished. Further studies with improved protocol and other parameters for outcome assessment are required to reach at definitive conclusion.

Keywords: homoeopathy; vitiligo; hypo-pigmented spots, Ars. sulph. flavum
R.V.R. Prasad, Ch. Raveender, Mrs. Bharatha Lakhsmi
Clinical Research Unit (Homoeopathy), Tirupathi, Andhra Pradesh

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Achyranthes aspera

Achyranthes aspera
 Achyranthes aspera commonly known as Latjira in Hindi, belongs to the family Amarantaceae; it is a small herb and very commonly found in India. The plant has been traditionally used for the treatment of boils, carbuncles, poisonous ulcers, diarrhoea and dysentery. The medicine was studied by CCRH in various potencies, viz. Q, 6c, 30c & 200c during the period 1984 – 2003. It was found that the drug was not only useful in clinical conditions like headache, painful aphthae, gastritis, intestinal colic, coryza, diarrhoea, dysentery, constipation, boils, abscess, acne, herpetic eruption, burning in whole body, cough, poisonous wounds, bad effects of insect bite and pyrexia as mentioned in homoeopathic literatures but also in blepharitis, worm complaints in children, colic, scabies, backache, pain in calf muscles and fistula etc., which can be inferred as its additional clinical symptoms as observed during the trial.

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Aegle marmelos

Aegle marmelos
Aegle marmelos, an indigenous plant of India , commonly known as bael in Hindi and belongs to the family Rutaca. It grows wild throughout India and its edible fruits are valued in indigenous medicine. The pulp of the fruit is stomachic, anti-microbial, digestive, astringent, spasmolytic and hypoglycemic as reported in various literatures. A study was conducted by CCRH over a period of 24 years (1980-2004) in various potencies , viz. Q, 6c and 30c to clinically verify the symptoms, which were found during the Homoeopathic Pathogenetic Trial carried out by the Council. It was evident from the trial that Aegle marmelos is having marked action in clinical conditions like styes, eye complaints, coryza, aphthae, pharyngitis, dysentery, backache, infective dermatitis, pain in calf, vertigo and pyrexia as reported in literatures and at the same time complaints like headache, anorexia, constipation and seminal emission etc., were also relieved during the trial, which can be inferred as additional clinical symptoms of the medicine.
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Boerhaavia diffusa

Boerhaavia diffusa
Boerhaavia diffusa commonly known as punarnava in Sanskrit, is a herbaceous plant of the family Nyctaginaceae and indigenous to India. The whole plant or its parts (leaves, stem & root) are known to have medicinal properties and have a long history of use by Indians, particularly the tribal people. The plant is widely used for the treatment of edema, dropsical condition and urinary troubles as reported in various literatures. A study was conducted by CCRH over a period of 24 years (1979-2003) at its various Institutes/Units in different potencies viz. Q, 6c & 30c to verify the symptoms, which were found during the Homoeopathic Pathogenetic Trial carried out by the Council. It was reflected from the study that Boerhaavia diffusa is a very effective medicine in relieving the clinical conditions like edema, hypertension, jaundice and nocturnal emission as reported in various literatures, but also in headache, coryza, vertigo, burning urination, leucorrhoea, menstrual irregularities, lumbago and pyrexia etc., which can be anecdoted as additional clinical symptoms as observed during the trial.
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